Deja Dup is a backup program that supports local and remote / cloud backups, which compresses and encrypts the data. Most of the work is done by duplicity, a command line backup tool for which Deja Dup acts as a graphical wrapper.
The application, which integrates tightly with the GNOME desktop, officially supports Google Drive and Nextcloud as cloud backup storage locations.
Unofficially though, Deja Dup also supports Amazon S3, Google Cloud Storage, Openstack Swift, and Rackspace Cloud Files services.
Backup to these cloud services has been marked as deprecated in Deja Dup, but there are no plans to drop support for them right now, and "for the foreseeable future, they are staying". They are, however, hidden by default.
Related: Securely And Efficiently Backup Data On Linux Or macOS With Vorta (BorgBackup GUI)
This article explains how to set up Deja Dup backup tool to take Linux desktop backups to Amazon S3.